Publication: Myoglobin for Detection of High-Risk Patients with Acute Myocarditis
Myoglobin for Detection of High-Risk Patients with Acute Myocarditis
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Kottwitz, J., Bruno, K. A., Berg, J., Salomon, G. R., Fairweather, D., Elhassan, M., Baltensperger, N., Kissel, C. K., Lovrinovic, M., Baltensweiler, A., Schmied, C., Templin, C., Lima, J. A. C., Landmesser, U., Lüscher, T. F., Manka, R., & Heidecker, B. (2020). Myoglobin for Detection of High-Risk Patients with Acute Myocarditis. Journal of Cardiovascular Translational Research, 13(5), 853–863. https://doi.org/10.1007/s12265-020-09957-8
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There is an unmet need for accurate and practical screening to detect myocarditis. We sought to test the hypothesis that the extent of acute myocarditis, measured by late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR), can be estimated based on routine blood markers. A total of 44 patients were diagnosed with acute myocarditis and included in this study. There was strong correlation between myoglobin and LGE (r${s}$ = 0.73 [95% CI 0.51; 0.87], p < 0.001), while correlation was weak between LGE and TnT-hs (r${s}$
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Kottwitz, J., Bruno, K. A., Berg, J., Salomon, G. R., Fairweather, D., Elhassan, M., Baltensperger, N., Kissel, C. K., Lovrinovic, M., Baltensweiler, A., Schmied, C., Templin, C., Lima, J. A. C., Landmesser, U., Lüscher, T. F., Manka, R., & Heidecker, B. (2020). Myoglobin for Detection of High-Risk Patients with Acute Myocarditis. Journal of Cardiovascular Translational Research, 13(5), 853–863. https://doi.org/10.1007/s12265-020-09957-8