Publication: The BDSF quorum sensing receptor RpfR regulates Bep exopolysaccharide synthesis in Burkholderia cenocepacia via interaction with the transcriptional regulator BerB
Date
Date
Date
2022
Journal Article
Published version
Abstract
Abstract
Abstract
The polysaccharide Bep is essential for in vitro biofilm formation of the opportunistic pathogen Burkholderia cenocepacia. We found that the Burkholderia diffusible signaling factor (BDSF) quorum sensing receptor RpfR is a negative regulator of the bep gene cluster in B. cenocepacia. An rpfR mutant formed wrinkled colonies, whereas additional mutations in the bep genes or known bep regulators like berA and berB restored the wild-type smooth colony morphology. We found that there is a good correlation between intracellular c-di-GMP lev
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Acq. date: 2025-11-13
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Additional indexing
Creators (Authors)
- Steiner, Elisabeth
- Shilling, Rebecca E
- Richter, Anja M
- Schmid, Nadine
- Fazli, Mustafa
- Kaever, Volkhard
- Jenal, Urs
- Tolker-Nielsen, Tim
Volume
Volume
Volume
8
Page range/Item number
Page range/Item number
Page range/Item number
93
Item Type
Item Type
Item Type
Journal Article
Keywords
Applied Microbiology and Biotechnology, Microbiology, Biotechnology
Language
Language
Language
English
Publication date
Publication date
Publication date
2022-11-22
Date available
Date available
Date available
2022-12-02
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
2055-5008
OA Status
OA Status
OA Status
Gold
Free Access at
Free Access at
Free Access at
Pubmed ID
Publisher DOI
Metrics
Downloads
5 since deposited on 2022-12-02
1last week
Acq. date: 2025-11-13
Views
2 since deposited on 2022-12-02
1last week
Acq. date: 2025-11-13
Gold Open Access
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