Publication: Analyses of circRNA Expression throughout the Light-Dark Cycle Reveal a Strong Regulation of Cdr1as, Associated with Light Entrainment in the SCN
Analyses of circRNA Expression throughout the Light-Dark Cycle Reveal a Strong Regulation of Cdr1as, Associated with Light Entrainment in the SCN
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Ivanov, A., Mattei, D., Radscheit, K., Compagnion, A.-C., Pett, J. P., Herzel, H., Paolicelli, R. C., Piwecka, M., Meyer, U., & Beule, D. (2022). Analyses of circRNA Expression throughout the Light-Dark Cycle Reveal a Strong Regulation of Cdr1as, Associated with Light Entrainment in the SCN. International Journal of Molecular Sciences, 23(20), 12347. https://doi.org/10.3390/ijms232012347
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Circular RNAs (circRNAs) are a large class of relatively stable RNA molecules that are highly expressed in animal brains. Many circRNAs have been associated with CNS disorders accompanied by an aberrant wake-sleep cycle. However, the regulation of circRNAs in brain homeostasis over daily light-dark (LD) cycles has not been characterized. Here, we aim to quantify the daily expression changes of circRNAs in physiological conditions in healthy adult animals. Using newly generated and public RNA-Seq data, we monitored circRNA expression t
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- Ivanov, Andranik
- Mattei, Daniele
- Radscheit, Kathrin
- Compagnion, Anne-Claire
- Pett, Jan Patrick
- Herzel, Hanspeter
- Paolicelli, Rosa Chiara
- Piwecka, Monika
- Meyer, Urs
- Beule, Dieter
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Ivanov, A., Mattei, D., Radscheit, K., Compagnion, A.-C., Pett, J. P., Herzel, H., Paolicelli, R. C., Piwecka, M., Meyer, U., & Beule, D. (2022). Analyses of circRNA Expression throughout the Light-Dark Cycle Reveal a Strong Regulation of Cdr1as, Associated with Light Entrainment in the SCN. International Journal of Molecular Sciences, 23(20), 12347. https://doi.org/10.3390/ijms232012347
