Publication: The primary cilium gene CPLANE1 is required for peripheral nervous system development
The primary cilium gene CPLANE1 is required for peripheral nervous system development
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Yusifov, E., Schaettin, M., Dumoulin, A., Bachmann-Gagescu, R., & Stoeckli, E. T. (2025). The primary cilium gene CPLANE1 is required for peripheral nervous system development. Developmental Biology, 519, 106–121. https://doi.org/10.1016/j.ydbio.2024.12.008
Abstract
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Abstract
Ciliopathies are a group of neurodevelopmental disorders characterized by the dysfunction of the primary cilium. This small protrusion from most cells of our body serves as a signaling hub for cell-to-cell communication during development. Cell proliferation, differentiation, migration, and neural circuit formation have been demonstrated to depend on functional primary cilia. In the context of ciliopathies, the focus has been on the development of the central nervous system, while the peripheral nervous system has not been studied in
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- Yusifov, Elkhan
- Schaettin, Martina
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Yusifov, E., Schaettin, M., Dumoulin, A., Bachmann-Gagescu, R., & Stoeckli, E. T. (2025). The primary cilium gene CPLANE1 is required for peripheral nervous system development. Developmental Biology, 519, 106–121. https://doi.org/10.1016/j.ydbio.2024.12.008
