Publication: Antigens of persistent Chlamydia pneumoniae within coronary atheroma from patients undergoing heart transplantation
Antigens of persistent Chlamydia pneumoniae within coronary atheroma from patients undergoing heart transplantation
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Borel, N., Pospischil, A., Dowling, R. D., Dumrese, C., Gaydos, C. A., Bunk, S., Hermann, C., Ramirez, J. A., & Summersgill, J. T. (2012). Antigens of persistent Chlamydia pneumoniae within coronary atheroma from patients undergoing heart transplantation. Journal of Clinical Pathology, 65, 171–177. https://doi.org/10.1136/jclinpath-2011-200270
Abstract
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AimsIn order for Chlamydia pneumoniae to play a causative role in chronic human disease, it would need to persist within infected tissue for extended periods of time. Current theory suggests that C pneumoniae may persist at the site of infection via an alternative replicative form, known as an aberrant body.MethodsA panel of C pneumoniae-specific antibodies upregulated by the aberrant body was used to probe tissue specimens from the coronary atheroma from 13 explanted hearts to identify patterns of reactivity in these tissues, as well
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Creators (Authors)
- Borel, Nicole
- Pospischil, A
- Dowling, R D
- Dumrese, C
- Gaydos, C A
- Bunk, S
- Hermann, C
- Ramirez, J A
- Summersgill, J T
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Citations
Borel, N., Pospischil, A., Dowling, R. D., Dumrese, C., Gaydos, C. A., Bunk, S., Hermann, C., Ramirez, J. A., & Summersgill, J. T. (2012). Antigens of persistent Chlamydia pneumoniae within coronary atheroma from patients undergoing heart transplantation. Journal of Clinical Pathology, 65, 171–177. https://doi.org/10.1136/jclinpath-2011-200270
