Publication: Prenatal immune activation causes hippocampal synaptic deficits in the absence of overt microglia anomalies
Prenatal immune activation causes hippocampal synaptic deficits in the absence of overt microglia anomalies
Date
Date
Date
Citations
Giovanoli, S., Weber-Stadlbauer, U., Schedlowski, M., Meyer, U., & Engler, H. (2016). Prenatal immune activation causes hippocampal synaptic deficits in the absence of overt microglia anomalies. Brain, Behavior, and Immunity, 55, 25–38. https://doi.org/10.1016/j.bbi.2015.09.015
Abstract
Abstract
Abstract
Prenatal exposure to infectious or inflammatory insults can increase the risk of developing neuropsychiatric disorder in later life, including schizophrenia, bipolar disorder, and autism. These brain disorders are also characterized by pre- and postsynaptic deficits. Using a well-established mouse model of maternal exposure to the viral mimetic polyriboinosinic-polyribocytidilic acid [poly(I:C)], we examined whether prenatal immune activation might cause synaptic deficits in the hippocampal formation of pubescent and adult offspring.
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Giovanoli, Sandra
- Weber-Stadlbauer, Ulrike
- Schedlowski, Manfred
- Meyer, Urs
- Engler, Harald
Volume
Volume
Volume
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Publisher DOI
Metrics
Downloads
Views
Citations
Giovanoli, S., Weber-Stadlbauer, U., Schedlowski, M., Meyer, U., & Engler, H. (2016). Prenatal immune activation causes hippocampal synaptic deficits in the absence of overt microglia anomalies. Brain, Behavior, and Immunity, 55, 25–38. https://doi.org/10.1016/j.bbi.2015.09.015
