Publication: Urinary pH and stone formation
Urinary pH and stone formation
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Wagner, C. A., & Mohebbi, N. (2010). Urinary pH and stone formation. Journal of Nephrology, 23 Sup, S165–S169.
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The formation of various types of kidney stones is strongly influenced by urinary pH. An alkaline pH favors the crystallization of calcium- and phosphate-containing stones, whereas and acidic urine pH promotes uric acid or cystine stones. The activity of many transport processes involved in calcium, citrate and phosphate handling are sensitive to changes in systemic or local pH as shown for several phosphate transporters, the citrate transporter NaDC1 and the TRPV5 calcium channel. Defects in urinary acidification (excretion of inappr
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- Wagner, C A
- Mohebbi, N
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Wagner, C. A., & Mohebbi, N. (2010). Urinary pH and stone formation. Journal of Nephrology, 23 Sup, S165–S169.
