Publication: The "Lost Caravaggio": a probable case of goiter in seventeenth-century Italy
The "Lost Caravaggio": a probable case of goiter in seventeenth-century Italy
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Traversari, M., Rühli, F. J., Gruppioni, G., & Galassi, F. M. (2016). The “Lost Caravaggio”: a probable case of goiter in seventeenth-century Italy. Journal of Endocrinological Investigation, 39(10), 1203–1204. https://doi.org/10.1007/s40618-016-0492-y
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Most human cancers, including myeloma, are preceded by a precursor state. There is an unmet need for in vivo models to study the interaction of human preneoplastic cells in the bone marrow microenvironment with non-malignant cells. Here, we genetically humanized mice to permit the growth of primary human preneoplastic and malignant plasma cells together with non-malignant cells in vivo. Growth was largely restricted to the bone marrow, mirroring the pattern in patients with myeloma. Xenografts captured the genomic complexity of parent
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Creators (Authors)
- Traversari, M
- Rühli, F J
- Gruppioni, G
- Galassi, F M
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Traversari, M., Rühli, F. J., Gruppioni, G., & Galassi, F. M. (2016). The “Lost Caravaggio”: a probable case of goiter in seventeenth-century Italy. Journal of Endocrinological Investigation, 39(10), 1203–1204. https://doi.org/10.1007/s40618-016-0492-y
