Publication: Intracerebral endotheliitis and microbleeds are neuropathological features of COVID‐19
Intracerebral endotheliitis and microbleeds are neuropathological features of COVID‐19
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Kirschenbaum, D., Imbach, L. L., Jane Rushing, E., Frauenknecht, K. B. M., Gascho, D., Victor Ineichen, B., Keller, E., Kohler, S., Lichtblau, M., Reimann, R. R., Schreib, K., Ulrich, S., Steiger, P., Aguzzi, A., & Frontzek, K. (2021). Intracerebral endotheliitis and microbleeds are neuropathological features of COVID‐19. Neuropathology and Applied Neurobiology, 47(3), 454–459. https://doi.org/10.1111/nan.12677
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Coronavirus disease 19 (COVID-19), caused by infection with the severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2), has become a worldwide pandemic (1). Symptoms of COVID-19 vary widely and range from asymptomatic disease to severe pneumonia and multiorgan failure (2). A severe disease course is more likely in older patients and patients with pre-existing respiratory and cardiovascular conditions (2). Patients with severe Sars-CoV-2 infection may present with ischaemic stroke (3, 4) or even fatal intracerebral haemorrhage (5
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Kirschenbaum, D., Imbach, L. L., Jane Rushing, E., Frauenknecht, K. B. M., Gascho, D., Victor Ineichen, B., Keller, E., Kohler, S., Lichtblau, M., Reimann, R. R., Schreib, K., Ulrich, S., Steiger, P., Aguzzi, A., & Frontzek, K. (2021). Intracerebral endotheliitis and microbleeds are neuropathological features of COVID‐19. Neuropathology and Applied Neurobiology, 47(3), 454–459. https://doi.org/10.1111/nan.12677