Publication: Control of protein and lipid composition of photoreceptor outer segments—Implications for retinal disease
Control of protein and lipid composition of photoreceptor outer segments—Implications for retinal disease
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Masek, M., & Bachmann-Gagescu, R. (2023). Control of protein and lipid composition of photoreceptor outer segments—Implications for retinal disease. In C. Iomini & Y. Sun (Eds.), Cilia Signaling in Development and Disease (No. 155; pp. 165–225). Elsevier. https://doi.org/10.1016/bs.ctdb.2023.09.001
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Vision is arguably our most important sense, and its loss brings substantial limitations to daily life for affected individuals. Light is perceived in retinal photoreceptors (PRs), which are highly specialized neurons subdivided into several compartments with distinct functions. The outer segments (OSs) of photoreceptors represent highly specialized primary ciliary compartments hosting the phototransduction cascade, which transforms incoming light into a neuronal signal. Retinal disease can result from various pathomechanisms originat
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Masek, M., & Bachmann-Gagescu, R. (2023). Control of protein and lipid composition of photoreceptor outer segments—Implications for retinal disease. In C. Iomini & Y. Sun (Eds.), Cilia Signaling in Development and Disease (No. 155; pp. 165–225). Elsevier. https://doi.org/10.1016/bs.ctdb.2023.09.001