Publication: A prospective cohort study on orally administered heroin substitution for severely addicted opioid users
A prospective cohort study on orally administered heroin substitution for severely addicted opioid users
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Frick, U., Rehm, J., Kovacic, S., Ammann, J., & Uchtenhagen, A. (2006). A prospective cohort study on orally administered heroin substitution for severely addicted opioid users. Addiction, 101(11), 1631–1639. https://doi.org/10.1111/j.1360-0443.2006.01569.x
Abstract
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Aims To assess the efficacy and safety of orally administered heroin [diacetylmorphine (DAM)] tablets in substitution treatment of severely addicted opioid users. Design An open-label, prospective cohort study with two non-randomly assigned treatment arms and historical controls: DAM tablets only versus DAM tablets combined with injected DAM and/or other opioids, with an observation period of 1 year. Setting Twenty-one out-patient treatment centres of the Swiss heroin-assisted treatment programme. Participants A total of 128 patie
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Citations
Frick, U., Rehm, J., Kovacic, S., Ammann, J., & Uchtenhagen, A. (2006). A prospective cohort study on orally administered heroin substitution for severely addicted opioid users. Addiction, 101(11), 1631–1639. https://doi.org/10.1111/j.1360-0443.2006.01569.x