Toothpastes with Enzymes Support Gum Health and Reduce Plaque Formation

Paqué, Pune N; Schmidlin, Patrick R; Wiedemeier, Daniel B; Wegehaupt, Florian J; Burrer, Phoebe D; Körner, Philipp; Deari, Shengjile; Sciotti, Michel-Angelo; Attin, Thomas

doi:10.3390/ijerph18020835

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Paqué, P. N., Schmidlin, P. R., Wiedemeier, D. B., Wegehaupt, F. J., Burrer, P. D., Körner, P., Deari, S., Sciotti, M.-A., & Attin, T. (2021). Toothpastes with Enzymes Support Gum Health and Reduce Plaque Formation. International Journal of Environmental Research and Public Health, 18, 835. https://doi.org/10.3390/ijerph18020835

Abstract

Enzymes in toothpastes can support host immune responses, and thus maintain oral health. This study aimed to investigate gingival health and the plaque-reducing effects of enzyme-containing toothpastes. A laboratory study tested the antimicrobial potential of different enzyme-containing toothpaste formulations. Two promising formulations (enzyme-containing toothpastes with glucose oxidase and D-glucose with (C+) and without Citrox (C-) Citrox) were investigated in a clinical crossover trial (two slurries: sodium lauryl sulfate-contain