Publication: Histone Ubiquitination: An Integrative Signaling Platform in Genome Stability
Histone Ubiquitination: An Integrative Signaling Platform in Genome Stability
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Mattiroli, F., & Penengo, L. (2021). Histone Ubiquitination: An Integrative Signaling Platform in Genome Stability. Trends in Genetics : Tig, 37(6), 566–581. https://doi.org/10.1016/j.tig.2020.12.005
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Complex mechanisms are in place to maintain genome stability. Ubiquitination of chromatin plays a central role in these mechanisms. The ever-growing complexity of the ubiquitin (Ub) code and of chromatin modifications and dynamics challenges our ability to fully understand how histone ubiquitination regulates genome stability. Here we review the current knowledge on specific, low-abundant histone ubiquitination events that are highly regulated within the cellular DNA damage response (DDR), with particular emphasis on the latest discov
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- Mattiroli, Francesca
- Penengo, Lorenza
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Mattiroli, F., & Penengo, L. (2021). Histone Ubiquitination: An Integrative Signaling Platform in Genome Stability. Trends in Genetics : Tig, 37(6), 566–581. https://doi.org/10.1016/j.tig.2020.12.005
