Publication: A genetic variation in the adenosine A2A receptor gene contributes to variability in oscillatory alpha power in wake and sleep EEG and A1 adenosine receptor availability in the human brain
A genetic variation in the adenosine A2A receptor gene contributes to variability in oscillatory alpha power in wake and sleep EEG and A1 adenosine receptor availability in the human brain
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Tichelman, N. L., Foerges, A. L., Elmenhorst, E.-M., Lange, D., Hennecke, E., Baur, D. M., Beer, S., Kroll, T., Neumaier, B., Bauer, A., Landolt, H.-P., Aeschbach, D., & Elmenhorst, D. (2023). A genetic variation in the adenosine A2A receptor gene contributes to variability in oscillatory alpha power in wake and sleep EEG and A1 adenosine receptor availability in the human brain. NeuroImage, 280, 120345. https://doi.org/10.1016/j.neuroimage.2023.120345
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The EEG alpha rhythm (∼ 8-13 Hz) is one of the most salient human brain activity rhythms, modulated by the level of attention and vigilance and related to cerebral energy metabolism. Spectral power in the alpha range in wakefulness and sleep strongly varies among individuals based on genetic predisposition. Knowledge about the underlying genes is scarce, yet small studies indicated that the variant rs5751876 of the gene encoding A$_{2A}$
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Tichelman, N. L., Foerges, A. L., Elmenhorst, E.-M., Lange, D., Hennecke, E., Baur, D. M., Beer, S., Kroll, T., Neumaier, B., Bauer, A., Landolt, H.-P., Aeschbach, D., & Elmenhorst, D. (2023). A genetic variation in the adenosine A2A receptor gene contributes to variability in oscillatory alpha power in wake and sleep EEG and A1 adenosine receptor availability in the human brain. NeuroImage, 280, 120345. https://doi.org/10.1016/j.neuroimage.2023.120345