Publication:

High-Throughput Miniaturized Biotransformation Testing Using Activated Sludge Enables Rapid Chemical Persistence Assessment

Date

Date

Date
2025
Journal Article
Published version

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Citation copied

Partanen, S. B., Mueller, N., & Fenner, K. (2025). High-Throughput Miniaturized Biotransformation Testing Using Activated Sludge Enables Rapid Chemical Persistence Assessment. Environmental Science & Technology Letters, 12, 1561–1566. https://doi.org/10.1021/acs.estlett.5c00859

Abstract

Abstract

Abstract

The unprecedented scale and pace of chemical development challenges human and ecosystem health unless new chemicals are developed using safe-by-design approaches. Therefore, tools for efficient environmental persistence assessmentamong other critical assessment capabilitiesare urgently needed, as outlined in the European Commission's Safe and Sustainable by Design (SSbD) framework and the European Chemical Agency (ECHA)'s 2025 report on key regulatory challenges. Current persistence tests require large sample amounts and extended ti

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Creators (Authors)

Journal/Series Title

Journal/Series Title

Journal/Series Title
Environmental Science & Technology Letters

Volume

Volume

Volume
12

Number

Number

Number
11

Page range/Item number

Page range/Item number

Page range/Item number
1561

Page end

Page end

Page end
1566

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

SSbD (Safe and Sustainable by Design), biodegradation, biotransformation, chemical screening, environmental fate, persistence assessment, well plates

Language

Language

Language
English

Publication date

Publication date

Publication date
2025-10-27

Date available

Date available

Date available
2026-02-06

Publisher

Publisher

Publisher
American Chemical Society (ACS)

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
2328-8930
2328-8930

OA Status

OA Status

OA Status
Hybrid

Free Access at

Free Access at

Free Access at
Unspecified

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PubMed ID

PubMed ID

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Citation copied

Partanen, S. B., Mueller, N., & Fenner, K. (2025). High-Throughput Miniaturized Biotransformation Testing Using Activated Sludge Enables Rapid Chemical Persistence Assessment. Environmental Science & Technology Letters, 12, 1561–1566. https://doi.org/10.1021/acs.estlett.5c00859

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