Publication: Preliminary Investigation of Side Effects of Polymyxin B Administration in Hospitalized Horses
Preliminary Investigation of Side Effects of Polymyxin B Administration in Hospitalized Horses
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Citations
van Spijk, J. N., Beckmann, K., Wehrli Eser, M., Stirn, M., Steuer, A. E., Saleh, L., & Schoster, A. (2023). Preliminary Investigation of Side Effects of Polymyxin B Administration in Hospitalized Horses. Antibiotics, 12(5), 854. https://doi.org/10.3390/antibiotics12050854
Abstract
Abstract
Abstract
Neuro- and nephrotoxicity of polymyxins are known but clinical studies in horses are lacking. The aim of this study was to describe neurogenic and nephrogenic side effects of hospitalized horses receiving Polymyxin B (PolyB) as part of their treatment plan. Twenty horses diagnosed with surgical colic (n = 11), peritonitis (n = 5), typhlocolitis (n = 2), pneumonia, and pyometra (each n = 1) were included. Antimicrobial treatment was randomized to GENTA (gentamicin 10 mg/kg bwt q24 h IV, penicillin 30.000 IU/kg q6 h IV) or NO GENTA (mar
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Creators (Authors)
- van Spijk, Julia N
- Wehrli Eser, Meret
- Stirn, Martina
- Steuer, Andrea E
- Saleh, Lanja
- Schoster, Angelika
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Citations
van Spijk, J. N., Beckmann, K., Wehrli Eser, M., Stirn, M., Steuer, A. E., Saleh, L., & Schoster, A. (2023). Preliminary Investigation of Side Effects of Polymyxin B Administration in Hospitalized Horses. Antibiotics, 12(5), 854. https://doi.org/10.3390/antibiotics12050854
