Publication: A Ru(II) polypyridyl complex bearing aldehyde functions as a versatile synthetic precursor for long-wavelength absorbing photodynamic therapy photosensitizers
A Ru(II) polypyridyl complex bearing aldehyde functions as a versatile synthetic precursor for long-wavelength absorbing photodynamic therapy photosensitizers
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Karges, J., Heinemann, F., Maschietto, F., Patra, M., Blacque, O., Ciofini, I., Spingler, B., & Gasser, G. (2019). A Ru(II) polypyridyl complex bearing aldehyde functions as a versatile synthetic precursor for long-wavelength absorbing photodynamic therapy photosensitizers. Bioorganic & Medicinal Chemistry, 27(12), 2666–2675. https://doi.org/10.1016/j.bmc.2019.05.011
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Abstract
The use of Photodynamic Therapy (PDT) for the treatment of several kinds of cancer as well as bacterial, fungal or viral infections has received increasing attention during the last decade. However, the currently clinically approved photosensitizers (PSs) have several drawbacks, including photobleaching, slow clearance from the organism and poor water solubility. To overcome these shortcomings, many efforts have been made in the development of new types of PSs, such as Ru(II) polypyridyl complexes. Nevertheless, most studied Ru(II) po
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- Karges, Johannes
- Heinemann, Franz
- Maschietto, Federica
- Patra, Malay
- Blacque, Olivier
- Ciofini, Ilaria
- Gasser, Gilles
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Karges, J., Heinemann, F., Maschietto, F., Patra, M., Blacque, O., Ciofini, I., Spingler, B., & Gasser, G. (2019). A Ru(II) polypyridyl complex bearing aldehyde functions as a versatile synthetic precursor for long-wavelength absorbing photodynamic therapy photosensitizers. Bioorganic & Medicinal Chemistry, 27(12), 2666–2675. https://doi.org/10.1016/j.bmc.2019.05.011
