Publication: Rationally Designed Long-Wavelength Absorbing Ru(II) Polypyridyl Complexes as Photosensitizers for Photodynamic Therapy
Rationally Designed Long-Wavelength Absorbing Ru(II) Polypyridyl Complexes as Photosensitizers for Photodynamic Therapy
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Karges, J., Heinemann, F., Jakubaszek, M., Maschietto, F., Subecz, C., Dotou, M., Vinck, R., Blacque, O., Tharaud, M., Goud, B., Viñuelas Zahínos, E., Spingler, B., Ciofini, I., & Gasser, G. (2020). Rationally Designed Long-Wavelength Absorbing Ru(II) Polypyridyl Complexes as Photosensitizers for Photodynamic Therapy. Journal of the American Chemical Society, 142(14), 6578–6587. https://doi.org/10.1021/jacs.9b13620
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Abstract
The utilization of photodynamic therapy (PDT) for the treatment of various types of cancer has gained increasing attention over the last decades. Despite the clinical success of approved photosensitizers (PSs), their application is sometimes limited due to poor water solubility, aggregation, photodegradation, and slow clearance from the body. To overcome these drawbacks, research efforts are devoted toward the development of metal complexes and especially Ru(II) polypyridine complexes based on their attractive photophysical and biolog
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- Karges, Johannes
- Heinemann, Franz
- Jakubaszek, Marta
- Maschietto, Federica
- Subecz, Chloé
- Dotou, Mazzarine
- Vinck, Robin
- Tharaud, Mickaël
- Goud, Bruno
- Viñuelas Zahínos, Emilio
- Ciofini, Ilaria
- Gasser, Gilles
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Karges, J., Heinemann, F., Jakubaszek, M., Maschietto, F., Subecz, C., Dotou, M., Vinck, R., Blacque, O., Tharaud, M., Goud, B., Viñuelas Zahínos, E., Spingler, B., Ciofini, I., & Gasser, G. (2020). Rationally Designed Long-Wavelength Absorbing Ru(II) Polypyridyl Complexes as Photosensitizers for Photodynamic Therapy. Journal of the American Chemical Society, 142(14), 6578–6587. https://doi.org/10.1021/jacs.9b13620
