Publication: The multimorbidity interaction severity index (MISI)
The multimorbidity interaction severity index (MISI)
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Gassmann, D., Cheetham, M., Siebenhuener, K., Holzer, B. M., Meindl-Fridez, C., Hildenbrand, F. F., Virgini, V., Martin, M., & Battegay, E. (2017). The multimorbidity interaction severity index (MISI). Medicine, 96(8), e6144. https://doi.org/10.1097/MD.0000000000006144
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Therapeutic decision-making for patients with multimorbidity (MM) is challenging. Clinical practice guidelines inadequately address harmful interactions and resulting therapeutic conflicts within and among diseases. A patient-specific measure of MM severity that takes account of this conflict is needed.As a proof of concept, we evaluated whether the new Multimorbidity Interaction Severity Index (MISI) could be used to reliably differentiate patients in terms of lower versus higher potential for harmful interactions.Two hypothetical pa
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Gassmann, D., Cheetham, M., Siebenhuener, K., Holzer, B. M., Meindl-Fridez, C., Hildenbrand, F. F., Virgini, V., Martin, M., & Battegay, E. (2017). The multimorbidity interaction severity index (MISI). Medicine, 96(8), e6144. https://doi.org/10.1097/MD.0000000000006144