Publication: 2,000 Year old β-thalassemia case in Sardinia suggests malaria was endemic by the Roman period
2,000 Year old β-thalassemia case in Sardinia suggests malaria was endemic by the Roman period
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Viganó, C., Haas, C., Rühli, F. J., & Bouwman, A. (2017). 2,000 Year old β-thalassemia case in Sardinia suggests malaria was endemic by the Roman period. American Journal of Physical Anthropology, 164(2), 362–370. https://doi.org/10.1002/ajpa.23278
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OBJECTIVES: The island of Sardinia has one of the highest incidence rates of β-thalassemia in Europe due to its long history of endemic malaria, which, according to historical records, was introduced around 2,600 years ago by the Punics and only became endemic around the Middle Ages. In particular, the cod39 mutation is responsible for more than 95% of all β-thalassemia cases observed on the island. Debates surround the origin of the mutation. Some argue that its presence in the Western Mediterranean reflects the migration of people a
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- Viganó, Claudia
- Haas, Cordula
- Rühli, Frank J
- Bouwman, Abigail
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Viganó, C., Haas, C., Rühli, F. J., & Bouwman, A. (2017). 2,000 Year old β-thalassemia case in Sardinia suggests malaria was endemic by the Roman period. American Journal of Physical Anthropology, 164(2), 362–370. https://doi.org/10.1002/ajpa.23278
