Left atrial appendage angiography is associated with the incidence and number of magnetic resonance imaging-detected brain lesions after percutaneous catheter-based left atrial appendage closure

Rillig, Andreas; Bellmann, Barbara; Skurk, Carsten; Leistner, David Manuel; Haeusler, Karl Georg; Lin, Tina; Geran, Rohat; Koehler, Luzie; Guttmann, Selma; Steffens, Daniel; Kasner, Mario; Jakob, Philipp; Tscholl, Verena; Roser, Mattias; Lenz, Klaus; Villringer, Kersten; Park, Jai-Wun; Fiebach, Jochen B; Landmesser, Ulf

doi:10.1016/j.hrthm.2017.11.015

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Rillig, A., Bellmann, B., Skurk, C., Leistner, D. M., Haeusler, K. G., Lin, T., Geran, R., Koehler, L., Guttmann, S., Steffens, D., Kasner, M., Jakob, P., Tscholl, V., Roser, M., Lenz, K., Villringer, K., Park, J.-W., Fiebach, J. B., & Landmesser, U. (2018). Left atrial appendage angiography is associated with the incidence and number of magnetic resonance imaging-detected brain lesions after percutaneous catheter-based left atrial appendage closure. Heart Rhythm, 15(1), 3–8. https://doi.org/10.1016/j.hrthm.2017.11.015

Abstract

BACKGROUND Percutaneous catheter-based left atrial appendage closure (LAAC) is a procedure being increasingly performed in patients with atrial fibrillation and high bleeding risk. OBJECTIVE The purpose of this study was to evaluate the incidence of magnetic resonance imaging (MRI)-detected acute brain lesions (ABLs) as well as potential changes in neurocognitive function after percutaneous LAAC in patients with atrial fibrillation. METHODS Brain MRI at 3 T was performed within 24 hours before and after LAAC along with neurologic (