Publication: AngiomiR-126 expression and secretion from circulating CD34+ and CD14+ PBMCs: role for pro-angiogenic effects and alterations in type-2 diabetics
AngiomiR-126 expression and secretion from circulating CD34+ and CD14+ PBMCs: role for pro-angiogenic effects and alterations in type-2 diabetics
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Mocharla, P., Briand, S., Giannotti, G., Dörries, C., Jakob, P., Paneni, F., Lüscher, T. F., & Landmesser, U. (2013). AngiomiR-126 expression and secretion from circulating CD34+ and CD14+ PBMCs: role for pro-angiogenic effects and alterations in type-2 diabetics. Blood, 121, 226–236. https://doi.org/10.1182/blood-2012-01-407106
Abstract
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Several peripheral blood mononuclear cell (PBMC)-derived cell populations can promote angiogenesis, and differences in CD34+ or CD14+ surface-expression have been used to separate PBMC-subpopulations in this respect. AngiomiRs, microRNAs regulating angiogenesis, have been identified as key regulators of angiogenic processes. The present study examines differential angiomiR-expression/secretion from CD34+/CD14+; CD34+/CD14-; CD34-/CD14+; CD34-/CD14- PBMC-subsets and their relevance for different pro-angiogenic properties. Notably, both
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- Mocharla, Pavani
- Briand, Sylvie
- Giannotti, Giovanna
- Dörries, Carola
- Jakob, Philipp
- Paneni, Francesco
- Lüscher, Thomas F
- Landmesser, Ulf
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Mocharla, P., Briand, S., Giannotti, G., Dörries, C., Jakob, P., Paneni, F., Lüscher, T. F., & Landmesser, U. (2013). AngiomiR-126 expression and secretion from circulating CD34+ and CD14+ PBMCs: role for pro-angiogenic effects and alterations in type-2 diabetics. Blood, 121, 226–236. https://doi.org/10.1182/blood-2012-01-407106
