Publication: Multiparametric imaging reveals that mitochondria-rich intercalated cells in the kidney collecting duct have a very high glycolytic capacity
Multiparametric imaging reveals that mitochondria-rich intercalated cells in the kidney collecting duct have a very high glycolytic capacity
Date
Date
Date
Citations
Ghazi, S., Bourgeois, S., Gomariz, A., Bugarski, M., Haenni, D., Martins, J. R., Nombela-Arrieta, C., Unwin, R. J., Wagner, C. A., Hall, A. M., & Craigie, E. (2020). Multiparametric imaging reveals that mitochondria-rich intercalated cells in the kidney collecting duct have a very high glycolytic capacity. FASEB Journal, 34, 8510–8525. https://doi.org/10.1096/fj.202000273R
Abstract
Abstract
Abstract
Alpha intercalated cells (αICs) in the kidney collecting duct (CD) belong to a family of mitochondria rich cells (MRCs) and have a crucial role in acidifying the urine via apical V-ATPase pumps. The nature of metabolism in αICs and its relationship to transport was not well-understood. Here, using multiphoton live cell imaging in mouse kidney tissue, FIB-SEM, and other complementary techniques, we provide new insights into mitochondrial structure and function in αICs. We show that αIC mitochondria have a rounded structure and are not
Metrics
Downloads
Views
Additional indexing
Creators (Authors)
- Ghazi, Susan
- Bourgeois, Soline
- Gomariz, Alvaro
- Bugarski, Milica
- Haenni, Dominik
- Martins, Joana R
- Nombela-Arrieta, César
- Unwin, Robert J
- Wagner, Carsten A
- Hall, Andrew M
- Craigie, Eilidh
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Publisher DOI
Metrics
Downloads
Views
Citations
Ghazi, S., Bourgeois, S., Gomariz, A., Bugarski, M., Haenni, D., Martins, J. R., Nombela-Arrieta, C., Unwin, R. J., Wagner, C. A., Hall, A. M., & Craigie, E. (2020). Multiparametric imaging reveals that mitochondria-rich intercalated cells in the kidney collecting duct have a very high glycolytic capacity. FASEB Journal, 34, 8510–8525. https://doi.org/10.1096/fj.202000273R
