Publication: Prion-like propagation as a pathogenic principle in frontotemporal dementia
Prion-like propagation as a pathogenic principle in frontotemporal dementia
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Hock, E.-M., & Polymenidou, M. (2016). Prion-like propagation as a pathogenic principle in frontotemporal dementia. Journal of Neurochemistry, 138 Supp, 163–183. https://doi.org/10.1111/jnc.13668
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Frontotemporal dementia is a devastating neurodegenerative disease causing stark alterations in personality and language. Characterized by severe atrophy of the frontal and temporal brain lobes, frontotemporal dementia (FTD) shows extreme heterogeneity in clinical presentation, genetic causes, and pathological findings. Like most neurodegenerative diseases, the initial symptoms of FTD are subtle, but increase in severity over time, as the disease progresses. Clinical progression is paralleled by exacerbation of pathological findings a
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- Hock, Eva-Maria
- Polymenidou, Magdalini
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Hock, E.-M., & Polymenidou, M. (2016). Prion-like propagation as a pathogenic principle in frontotemporal dementia. Journal of Neurochemistry, 138 Supp, 163–183. https://doi.org/10.1111/jnc.13668
