Impact of comorbidities at diagnosis on the 10-year colorectal cancer net survival: A population-based study

Michalopoulou, Eleftheria; Matthes, Katarina Luise; Karavasiloglou, Nena; Wanner, Miriam; Limam, Manuela; Korol, Dimitri; Held, Leonhard; Rohrmann, Sabine

doi:10.1016/j.canep.2021.101962

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Michalopoulou, E., Matthes, K. L., Karavasiloglou, N., Wanner, M., Limam, M., Korol, D., Held, L., & Rohrmann, S. (2021). Impact of comorbidities at diagnosis on the 10-year colorectal cancer net survival: A population-based study. Cancer Epidemiology, 73, 101962. https://doi.org/10.1016/j.canep.2021.101962

Abstract

Background

It is established that comorbidities negatively influence colorectal cancer (CRC)-specific survival. Only few studies have used the relative survival (RS) setting to estimate this association, although RS has been proven particularly useful considering the inaccuracy in death certification. This study aimed to investigate the impact of non-cancer comorbidities at CRC diagnosis on net survival, using cancer registry data. Methods

We included 1076 CRC patients diagnosed between 2000 and 2001 in the canton of Zurich. The num