Publication: Broadening the chemical diversity of oxidovanadium(V) complexes for targeting neglected tropical diseases
Broadening the chemical diversity of oxidovanadium(V) complexes for targeting neglected tropical diseases
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Scalese, G., Pérez, N., Pereyra, J., Sanabria, Y., Blacque, O., Pérez-Díaz, L., & Gambino, D. (2025). Broadening the chemical diversity of oxidovanadium(V) complexes for targeting neglected tropical diseases. Journal of Inorganic Biochemistry, 269, 112891. https://doi.org/10.1016/j.jinorgbio.2025.112891
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Chagas disease and Leishmaniasis, caused by Trypanosoma cruzi and Leishmania spp., respectively, are highly prevalent neglected tropical diseases (NTDs) that pose significant global health challenges. In our pursuit of effective vanadium-based therapeutics against these diseases, we previously developed several series of oxidovanadium(V) complexes featuring bidentate bioactive ligands and Schiff base tridentate ligands. The current study extends our previous research by incorporating in the same molecule, a tridentate bromo-substitute
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Scalese, G., Pérez, N., Pereyra, J., Sanabria, Y., Blacque, O., Pérez-Díaz, L., & Gambino, D. (2025). Broadening the chemical diversity of oxidovanadium(V) complexes for targeting neglected tropical diseases. Journal of Inorganic Biochemistry, 269, 112891. https://doi.org/10.1016/j.jinorgbio.2025.112891