Driven by the proliferation of digital media, citizen science – the involvement of non-scientists in scientific research – represents one of the most important recent developments in science communication as it brings science and the public closer together. So far, however, citizen science projects have mostly attracted people that are highly educated, mostly male and already have very positive attitudes towards science. Based on nationally representative survey data (N = 1051), our study explores the potential of citizen science in Switzerland. Using regression analysis, we show that attitudes towards science are significant antecedents of respondents’ interest in participating in citizen science – but that gender and education are not. In addition, latent class analysis identifies five segments, representing over one-third of the Swiss population, who are interested in citizen science and could potentially be engaged: ‘Free-Timers’, ‘Senior Sciencephiles’, ‘Young Sciencephiles’, ‘Intrigued Adolescents’ and ‘Fully Employed Parents’. Additional description suggests that previously overlooked segments are best addressed online via YouTube or offline in zoos or botanical gardens. Overall, our analysis suggests that citizen science’s potential is far higher than previous projects were able to realize.